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SkinCeuticals

A.G.E. Interrupter Advanced

A.G.E. Interrupter Advanced

Regular price $185.00 USD
Regular price Sale price $185.00 USD
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Backed by 15+ years of glycation research and expertise, A.G.E. Interrupter Advanced is a breakthrough in corrective cream technology, clinically proven to smooth visible lines and wrinkles in five facial zones targeted for aesthetic procedures. Formulated with 18% concentrated Proxylane, 4.25% wild fruit flavonoid blend of blueberry and pomegranate extracts, and 0.1% glycyrrhetinic acid, this potent treatment helps correct and defend against visible signs of accelerated aging impacted by glycation and collagen decline.

  • Helps address the complete multi-phase glycation process known to visibly age skin
  • After 12 weeks, A.G.E. Interrupter Advanced improved the appearance of fine lines and deep wrinkles in five key facial zones targeted for aesthetic procedures⁶

    –After 12 weeks, A.G.E. Interrupter Advanced demonstrated a clinically significant improvement in density of the skin5
    –After 5 days, A.G.E. Interrupter Advanced showed reduction of advanced glycation end-products by 34.1% in vivo1
    –After 12 weeks, A.G.E. Interrupter Advanced increased filaggrin by 92% in vivo4
     
  • Delivers rich hydration, with a luxurious, satin finish
  • Free of parabens, drying alcohol, and dyes

 

REDUCES SIGNS OF AGING & GLYCATION  
After 12 weeks, A.G.E. Interrupter Advanced improved attributes associated with the appearance of skin aging and glycation, including lines and deep wrinkles in multiple facial zones targeted for aesthetic procedures.

14% global fine lines1

11% forehead wrinkles1

11% nasolabial folds1

7% marionette wrinkles1

7% glabellar wrinkles1

7% crow’s feet1

Increased total skin density5

24-hour hydration1

6Protocol: A 12-week, single-center, clinical study was conducted on 77 females with Fitzpatrick type I-VI, ages 38-70, and mild to moderate global wrinkles, fine lines, laxity, rough skin texture, uneven skin tone, and a dull complexion. A.G.E Interrupter Advanced was used twice daily over face, neck and chest in conjunction of a sunscreen for 12 weeks. Efficacy and tolerance evaluations were conducted at baseline, weeks 4, 8, and 12.  

7A 24-hour, single-center, clinical study was conducted on 29 subjects. A.G.E Interrupter Advanced was applied once on a forearm test zone. An untreated zone served as control. Corneometer readings were conducted on the test zones at baseline, immediate, hours 2, 8, and 24.

 

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After Use

Use

Twice daily, massage a thin, even layer of A.G.E. Interrupter Advanced onto the entire face, neck, and chest. If using in the morning, apply after a SkinCeuticals vitamin C antioxidant serum and before a SkinCeuticals sunscreen. If using with a retinol at night, apply after retinol application.

Homecare Regimen


AM REGIMEN:
  • APPLY 3-5 DROPS OF C E FERULIC TO A DRY FACE, NECK, AND CHEST.
  • APPLY 4-6 DROPS OF H.A. INTENSIFIER TO FOREHEAD, CHEEKS, CHIN, AND NECK.
  • APPLY A THIN, EVEN LAYER OF A.G.E. INTERRUPTER ADVANCED TO THE ENTIRE FACE, NECK, AND CHEST.
  • APPLY A GENEROUS AMOUNT OF PHYSICAL FUSION UV DEFENSE SPF 30 TO FACE, NECK, AND CHEST.

PM REGIMEN:
  • GENTLY CLEANSE FACE WITH A SKINCEUTICALS CLEANSER.
  • APPLY 1-2 PUMPS OF RESVERATROL B E TO A DRY FACE, NECK, AND CHEST.
  • APPLY 4-6 DROPS OF H.A. INTENSIFIER TO FOREHEAD, CHEEKS, CHIN, AND NECK.
  • APPLY A THIN, EVEN LAYER OF A.G.E. INTERRUPTER ADVANCED TO THE ENTIRE FACE, NECK, AND CHEST.

Key Ingredients

 

18% CONCENTRATED PROXYLANETM
Helps correct visible wrinkles and laxity by stimulating collagen VII and supporting its environment, delivering 6x more than the minimum effective dose known to initiate the synthesis of glycosaminoglycans (GAGs).

4.25% WILD FRUIT FLAVONOIDS
Antioxidant blend of blueberry and pomegranate extracts helps inhibit protein glycation, including UV-induced glycation, and protect against free radical damage.

0.1% GLYCYRRHETININIC ACID
Therapeutic anti-inflammatory helps enhance the skin’s natural radiance to counter dull and sallow tone, which may be linked to A.G.E. accumulation.

3% HEPES
Normalizes epidermal renewal to resurface the skin, encourages new cell migration to the skin’s surface, replenishes moisture levels and reinforces the skin's barrier.

1% NIACINAMIDE
Supports the skin’s barrier, helps improve the appearance of discoloration, stimulates cellular turnover, and helps fortify the skin’s supportive protein matrix.

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